故事讲述在距离地球2032万光年的地方有一颗名叫星梦花园的星球，星球上住着十二位美德星使及一群信奉美德的居民。星梦花园应美德而声名远播，各个星球的人们都喜欢来此旅游。星梦花园的居民们希望把十二种美德传播到整个宇宙，所以建立了星愿学院，让外星球的孩子们来此学习，学习为期一年。 在第一部的《星与星愿》中，星愿学院迎来了它的第一批学生——五位性格各异的星愿宝贝，他们将在积木哥哥、花瓣姐姐、奶瓶阿姨、BB床大叔、百科全书校长的教导下学习知识，并在十二位美德星使的引导下学习美德、争取美德之星。 十二位美德星使各自掌管着一种美德，当星愿宝贝学会一项美德时，美德星使将为他颁发对应的美德之星，美德之星包括：聪明之星、感恩之星、环保之星、健康之星、节约之星、勤奋之星、善良之星、勇敢之星、正义之星、自律之星。
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